The global pandemic may be over, but SARS-CoV-2 continues to infect people around the world. Indeed, the United States has recorded roughly 750 deaths from COVID-19 over the past month. Now, an siRNA ...

Routine genomic surveillance in California uncovered a rare 69-nucleotide in-frame deletion in the SARS-CoV-2 nsp3 protein, ...

Scientists have identified dozens of human proteins that SARS-CoV-2, the virus that causes COVID-19, depends on to replicate and spread, according to a recent study published in the journal PLOS ...

Viruses can re-structure the architecture of host cells genome and also alter their epigenomic landscape. In this study, we investigate with polymer physics modelling virus induced genome ...

Despite vaccines and treatments, SARS-CoV-2-the virus that causes COVID-19-continues to pose a global health threat, driven by new variants and its ability to hijack human cells in ways that still ...

Researchers at Karolinska Institutet have discovered how the SARS-CoV-2 virus, which causes COVID-19, manipulates human proteins to replicate and evade the immune system. The results have been ...

A research team at Ruhr University Bochum, Germany, has identified a previously unknown cellular mechanism crucial to the replication of coronaviruses: c-Jun N-terminal kinase (JNK) is activated ...

A study led by the University of Barcelona and the Spanish National Research Council's Institute for Advanced Chemistry of Catalonia (IQAC - CSIC) presents a new therapeutic tool capable of inhibiting ...

UCSF researchers designed new drug candidates that potently block MPro, a viral enzyme that's crucial for SARS-CoV-2 replication. One of these drug candidates, AVI-4516, is shown (center) bound to the ...